1CBW

BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI

Summary for 1CBW

Entry DOI	10.2210/pdb1cbw/pdb
Descriptor	BOVINE CHYMOTRYPSIN, BPTI, SULFATE ION, ... (6 entities in total)
Functional Keywords	serine protease, inhibitor, protease-substrate interactions, complex (serine protease-inhibitor), complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor)
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00767 P00766 P00766 Secreted: P00974
Total number of polymer chains	8
Total formula weight	63772.39
Authors	Hynes, T.R.,Scheidig, A.J.,Kossiakoff, A.A. (deposition date: 1996-12-22, release date: 1997-07-23, Last modification date: 2023-08-09)
Primary citation	Scheidig, A.J.,Hynes, T.R.,Pelletier, L.A.,Wells, J.A.,Kossiakoff, A.A. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci., 6:1806-1824, 1997 Cited by PubMed: 9300481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation