1AXE

CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL

Summary for 1AXE

Entry DOI	10.2210/pdb1axe/pdb
Descriptor	ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	oxidoreductase (nad(a)-choh(d)), alcohol dehydrogenase, oxidoreductase
Biological source	Equus caballus (horse)
Cellular location	Cytoplasm: P00327
Total number of polymer chains	2
Total formula weight	81573.18
Authors	Colby, T.D.,Chin, J.K.,Goldstein, B.M. (deposition date: 1997-10-15, release date: 1998-04-15, Last modification date: 2023-08-02)
Primary citation	Bahnson, B.J.,Colby, T.D.,Chin, J.K.,Goldstein, B.M.,Klinman, J.P. A link between protein structure and enzyme catalyzed hydrogen tunneling. Proc.Natl.Acad.Sci.USA, 94:12797-12802, 1997 Cited by PubMed: 9371755 DOI: 10.1073/pnas.94.24.12797 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation