1AXE

CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL

Summary for 1AXE

DescriptorALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywordsoxidoreductase (nad(a)-choh(d)), alcohol dehydrogenase, oxidoreductase
Biological sourceEquus caballus (horse)
Cellular locationCytoplasm P00327
Total number of polymer chains2
Total molecular weight81573.18
Authors
Colby, T.D.,Chin, J.K.,Goldstein, B.M. (deposition date: 1997-10-15, release date: 1998-04-15, Last modification date: 2011-07-13)
Primary citation
Bahnson, B.J.,Colby, T.D.,Chin, J.K.,Goldstein, B.M.,Klinman, J.P.
A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc.Natl.Acad.Sci.USA, 94:12797-12802, 1997
PubMed: 9371755 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.94.24.12797
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23060.3%2.9%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution