6Y2Y

The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with Trp51 to S-Trp51 and Trp191Phe modifications

Summary for 6Y2Y

Entry DOI	10.2210/pdb6y2y/pdb
Descriptor	Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	peroxidase, heme, engineered, non-canonical amino acid, oxidoreductase
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains	1
Total formula weight	37587.45
Authors	Ortmayer, M.,Levy, C.,Green, A.P. (deposition date: 2020-02-17, release date: 2021-06-16, Last modification date: 2024-01-24)
Primary citation	Ortmayer, M.,Hardy, F.J.,Quesne, M.G.,Fisher, K.,Levy, C.,Heyes, D.J.,Catlow, C.R.A.,de Visser, S.P.,Rigby, S.E.J.,Hay, S.,Green, A.P. A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase. Jacs Au, 1:913-918, 2021 Cited by PubMed: 34337604 DOI: 10.1021/jacsau.1c00145 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation