8YCP

structure of human trpv1 in complex with BC5

This is a non-PDB format compatible entry.

Summary for 8YCP

• Entry DOI: 10.2210/pdb8ycp/pdb
• EMDB information: 39151
• Descriptor: Transient receptor potential cation channel subfamily V member 1, (1~{R},2~{S})-1-butyl-~{N}-(2,6-dimethylphenyl)-1-[5-[(2~{S})-2-[(2,6-dimethylphenyl)carbamoyl]piperidin-1-yl]pentyl]piperidin-1-ium-2-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, ... (4 entities in total)
• Functional Keywords: ion channel, membrane protein, cryo-em
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 306486.56

Authors

Ke, B.W.,Hu, S.L. (deposition date: 2024-02-18, release date: 2025-01-29)

• Primary citation: Hu, S.L.,Wenrui, G.; Sequential multitarget modulation: Developing Ultra-long-acting sensory-specific local anesthetics for postoperative pain; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.87 Å)