2H6U

Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)

Summary for 2H6U

Related2H1X 1F41
Descriptor5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) (2 entities in total)
Functional Keywords5-hydroxyisourate hydrolase, trp, uric acid degradation, allantoin, hydrolase
Biological sourceDanio rerio (zebrafish)
Total number of polymer chains8
Total molecular weight106081
Authors
Zanotti, G.,Cendron, L.,Folli, C.,Ramazzina, I.,Percudani, R.,Berni, R. (deposition date: 2006-06-01, release date: 2006-10-31, Last modification date: 2011-07-13)
Primary citation
Zanotti, G.,Cendron, L.,Ramazzina, I.,Folli, C.,Percudani, R.,Berni, R.
Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363:1-9, 2006
PubMed: 16952372 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2006.07.079
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25280.1%2.2%3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2h6u
no rotation
Molmil generated image of 2h6u
rotated about x axis by 90°
Molmil generated image of 2h6u
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2h6u
no rotation
Molmil generated image of 2h6u
rotated about x axis by 90°
Molmil generated image of 2h6u
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2h6u.pdb2.gz [79.7 KB])
Coordinate files for Biological unit (2h6u.pdb1.gz [81.32 KB])