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1R4F

Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine

Summary for 1R4F
Entry DOI10.2210/pdb1r4f/pdb
Related1HOZ 1HP0 1KIC 1KIE 1MAS 2MAS
DescriptorIAG-nucleoside hydrolase, CALCIUM ION, 3-DEAZA-ADENOSINE, ... (4 entities in total)
Functional Keywordsrossmann fold, aromatic stacking, hydrolase
Biological sourceTrypanosoma vivax
Total number of polymer chains2
Total formula weight75554.11
Authors
Versees, W.,Loverix, S.,Vandemeulebroucke, A.,Geerlings, P.,Steyaert, J. (deposition date: 2003-10-06, release date: 2004-04-13, Last modification date: 2023-08-23)
Primary citationVersees, W.,Loverix, S.,Vandemeulebroucke, A.,Geerlings, P.,Steyaert, J.
Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338:1-6, 2004
Cited by
PubMed: 15050818
DOI: 10.1016/j.jmb.2004.02.049
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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