1R4F
Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | IAG-nucleoside hydrolase | polymer | 339 | 37603.9 | 2 | UniProt (Q9GPQ4) | Trypanosoma vivax | |
| 2 | C, D (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 3 | E (B) | 3-DEAZA-ADENOSINE | non-polymer | 266.3 | 1 | Chemie (AD3) PubChem (1651) PubChem (23190) PubChem (176735355) PubChem (177678932) PubChem (29976739) PubChem (29976742) PubChem (44386188) PubChem (45038778) PubChem (46873944) PubChem (44367024) PubChem (688459) PubChem (46937005) PubChem (59036309) PubChem (92852183) PubChem (93055319) PubChem (94199777) PubChem (12769724) PubChem (12769725) PubChem (124423261) PubChem (134692539) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 327 (UniProt: Q9GPQ4)
| PDB | External Database | Details |
|---|---|---|
| Met -12 | - | expression tag |
| Arg -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Pro -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 259 | Trp 260 | engineered mutation |
| Asn 214 | Lys 301 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75207.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 346.4 | |
| All* | Total formula weight | 75554.1 |
