1R4F

Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	IAG-nucleoside hydrolase	polymer	339	37603.9	2	UniProt (Q9GPQ4) Pfam (PF01156)	Trypanosoma vivax
2	C, D (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	E (B)	3-DEAZA-ADENOSINE	non-polymer		266.3	1	Chemie (AD3)
4	F, G (A, B)	water	water		18.0	163	Chemie (HOH)

Sequence modifications

A, B: 2 - 327 (UniProt: Q9GPQ4)

PDB	External Database	Details
Met -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Pro -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 259	Trp 260	engineered mutation
Asn 214	Lys 301	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75207.7
Non-Polymers*	Number of molecules	3
	Total formula weight	346.4
All*	Total formula weight	75554.1

*Water molecules are not included.