7LKI

The crystal structure of Epitope III of HCV envelop protein E2 in complex with antibody 1H8

This is a non-PDB format compatible entry.

Summary for 7LKI

• Entry DOI: 10.2210/pdb7lki/pdb
• Descriptor: antibody 1H8 heavy chain, antibody 1H8 light chain, Epitope III peptide GLY-ALA-PRO-THR-TYR-SER-TRP-GLY, ... (4 entities in total)
• Functional Keywords: hcv, envelope protein e2, virus
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 97730.88

Authors

Deng, L.,Zhang, P. (deposition date: 2021-02-02, release date: 2021-08-04, Last modification date: 2023-10-18)

• Primary citation: Deng, L.,Hernandez, N.,Zhong, L.,Holcomb, D.D.,Yan, H.,Virata, M.L.,Tarafdar, S.,Xu, Y.,He, Y.,Struble, E.,Alter, H.J.,Zhang, P.; A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34260404; DOI: 10.1073/pnas.2104242118

Experimental method

X-RAY DIFFRACTION (2 Å)