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6CK9	Crystal Structure of HIV-1 ConC_Base0 Prefusion Env Trimer in Complex with Human Antibody Fragment 3H109L and 35O22 variants at 3.5 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lai, Y.-T, Kwong, P.D. Deposit date: 2018-02-27 Release date: 2018-04-25 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.714 Å) Cite: A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers. Cell Rep, 23, 2018
7M6D	Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022 Descriptor: BG4-25 Fab Heavy Chain, BG4-25 Fab Light Chain, CR3022 Fab Heavy Chain, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2021-03-25 Release date: 2021-05-05 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV. Cell, 184, 2021
8TFN	Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR Descriptor: Anti-TCRVb6-5 Fab heavy chain, Anti-TCRVb6-5 Fab light chain, TRAV12-3, ... Authors: Katragadda, M, Servatalab, R, Wirth, J. Deposit date: 2023-07-11 Release date: 2023-11-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9, 2023
7T17	Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment Descriptor: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ... Authors: Miller, A.S, Kuhn, R.J. Deposit date: 2021-12-01 Release date: 2022-11-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (5.26 Å) Cite: A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization. Cell, 185, 2022
7TDM	CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain Descriptor: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ... Authors: Vecchio, A.J. Deposit date: 2022-01-01 Release date: 2022-02-09 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J.Biol.Chem., 298, 2022
7TDN	CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain Descriptor: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ... Authors: Vecchio, A.J. Deposit date: 2022-01-01 Release date: 2022-02-09 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (5 Å) Cite: Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J.Biol.Chem., 298, 2022
8PKC	Structure of Api m1 in complex with the AM1-4 nanobody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM1-4 nanobody, Phospholipase A2 Authors: Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M. Deposit date: 2023-06-26 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1 To be published
8PIH	Structure of Api m1 in complex with two nanobodies Descriptor: CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ... Authors: Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R. Deposit date: 2023-06-21 Release date: 2024-05-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1 To be published
8PMX	rat HEV P domain in complex with glycan-sensitive nAb p60.12 Descriptor: Fab p60.12-HC, Fab p60.12-LC, Pro-secreted protein ORF2 Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (3.922 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PMW	HEV gt3 P domain in complex with glycan-sensitive nAb p60.1 Descriptor: ACETATE ION, Capsid protein, SULFATE ION, ... Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PN0	HEV gt3 P domain in complex with glycan-sensitive nAb p60.12 Descriptor: Capsid protein, Fab_p60.12-HC, Fab_p60.12-LC Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.072 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PMY	HEV gt3 P domain in complex with glycan-insensitive nAb p60.15 Descriptor: Capsid protein, ZINC ION, scFv_p60.15 Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.406 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PMZ	HEV gt3 P domain in complex with glycan-insensitive nAb p61.15 Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-secreted protein ORF2, scFv_p61.15 Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.912 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
4HH9	Anti-Human Cytomegalovirus (HCMV) Fab KE5 Descriptor: Fab KE5, heavy chain, light chain Authors: Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Pfoh, R, Schrader, J.W, Pai, E.F. Deposit date: 2012-10-09 Release date: 2013-10-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. J. Immunol., 196, 2016
4HIJ	Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound L-rhamnose-(1-2)-alpha-D-galactose-(3-O)-phosphate-2-glycerol Descriptor: Fab 023.102 heavy chain, Fab 023.102 light chain, GLYCEROL, ... Authors: Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. Deposit date: 2012-10-11 Release date: 2013-08-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. J. Immunol., 196, 2016
4HII	Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound rhamnose-galactose Descriptor: Fab 023.102 heavy chain, Fab 023.102 light chain, alpha-L-rhamnopyranose-(1-2)-beta-D-galactopyranose Authors: Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. Deposit date: 2012-10-11 Release date: 2013-08-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. J. Immunol., 196, 2016
6OC8	Crystal structure of a VHH against the capsid protein from BLV Descriptor: GLYCEROL, SULFATE ION, VHH8c Authors: Carrion, F, Larrieux, N, Trajtenberg, F, Buschiazzo, A. Deposit date: 2019-03-22 Release date: 2020-03-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.109 Å) Cite: BLV capsid self-assembly inhibition by heavy chain antibodies To be Published
6O8D	Anti-CD28xCD3 CODV Fab bound to CD28 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-CD28xCD3 CODV Fab Heavy chain, ... Authors: Lord, D.M, Wei, R.R. Deposit date: 2019-03-09 Release date: 2019-11-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.547 Å) Cite: Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation To Be Published
7PA9	JC polyomavirus VP1 in complex with Fab 98D3 Descriptor: Fab 98D3 VH, Fab 98D3 VL, Major capsid protein VP1 Authors: Stroeh, L.J, Harprecht, C, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7PA8	JC polyomavirus VP1 in complex with Fab 27C2 Descriptor: Fab 27C2 heavy chain, Fab 27C2 light chain, Major capsid protein VP1 Authors: Stroeh, L.J, Harprecht, C, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7PAA	JC polyomavirus VP1 in complex with scFv 29B1 Descriptor: Major capsid protein VP1, scFv 29B1 Authors: Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
5UTF	Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Heavy chain, ... Authors: Pancera, M, Chuang, G.-Y, Xu, K, Kwong, P.D. Deposit date: 2017-02-14 Release date: 2017-03-29 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.503 Å) Cite: Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. J. Virol., 91, 2017
5UTY	Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ... Authors: Xu, K, Chuang, G.-Y, Pancera, M, Kwong, P.D. Deposit date: 2017-02-15 Release date: 2017-03-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.412 Å) Cite: Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. J. Virol., 91, 2017
6CEZ	Crystal Structure of Rabbit Anti-HIV-1 gp120 V2 Fab 16C2 in complex with V2 peptide ConB Descriptor: HIV-1 gp120 V2 Peptide Con B, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, Light chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2 Authors: Kong, X, Pan, R. Deposit date: 2018-02-13 Release date: 2018-09-12 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.399 Å) Cite: Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha 4 beta 7. PLoS Pathog., 14, 2018
6VRY	Structure of NCI09 fab in complex with SIV V2 peptide Descriptor: NCI09 heavy chain, NCI09 light chain, SIV V2 peptide, ... Authors: Gorman, J, Ahmadi, M, Kwong, P.D. Deposit date: 2020-02-10 Release date: 2020-12-30 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.4 Å) Cite: HIV vaccine candidate with V1 deletion reveals virus vulnerability to V2 antibodies Iscience, 2020

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