7M6D

Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022

Summary for 7M6D

• Entry DOI: 10.2210/pdb7m6d/pdb
• Descriptor: CR3022 Fab Heavy Chain, CR3022 Fab Light Chain, Spike protein S1, ... (6 entities in total)
• Functional Keywords: sars-cov-2, coronavirus, covid-19, antibody, neutralizing antibody, receptor binding domain, spike glycoprotein, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 120291.29

Authors

Barnes, C.O.,Bjorkman, P.J. (deposition date: 2021-03-25, release date: 2021-05-05, Last modification date: 2023-10-18)

• Primary citation: Scheid, J.F.,Barnes, C.O.,Eraslan, B.,Hudak, A.,Keeffe, J.R.,Cosimi, L.A.,Brown, E.M.,Muecksch, F.,Weisblum, Y.,Zhang, S.,Delorey, T.,Woolley, A.E.,Ghantous, F.,Park, S.M.,Phillips, D.,Tusi, B.,Huey-Tubman, K.E.,Cohen, A.A.,Gnanapragasam, P.N.P.,Rzasa, K.,Hatziioanno, T.,Durney, M.A.,Gu, X.,Tada, T.,Landau, N.R.,West Jr., A.P.,Rozenblatt-Rosen, O.,Seaman, M.S.,Baden, L.R.,Graham, D.B.,Deguine, J.,Bieniasz, P.D.,Regev, A.,Hung, D.,Bjorkman, P.J.,Xavier, R.J.; B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.; Cell, 184:3205-, 2021; PubMed: 34015271; DOI: 10.1016/j.cell.2021.04.032

Experimental method

X-RAY DIFFRACTION (3.1 Å)