8TFN

Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR

Summary for 8TFN

Entry DOI	10.2210/pdb8tfn/pdb
Descriptor	TRAV12-3, TRBV6-5, Anti-TCRVb6-5 Fab heavy chain, ... (5 entities in total)
Functional Keywords	tcr, anti-tcr, trbv12-3, trbv6-5, complex structure, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	97122.98
Authors	Katragadda, M.,Servatalab, R.,Wirth, J. (deposition date: 2023-07-11, release date: 2023-11-08, Last modification date: 2024-05-22)
Primary citation	Vantourout, P.,Eum, J.,Conde Poole, M.,Hayday, T.S.,Laing, A.G.,Hussain, K.,Nuamah, R.,Kannambath, S.,Moisan, J.,Stoop, A.,Battaglia, S.,Servattalab, R.,Hsu, J.,Bayliffe, A.,Katragadda, M.,Hayday, A.C. Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9:eadj6174-eadj6174, 2023 Cited by PubMed: 38055824 DOI: 10.1126/sciadv.adj6174 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.54 Å)

Structure validation