8PMZ

HEV gt3 P domain in complex with glycan-insensitive nAb p61.15

Summary for 8PMZ

• Entry DOI: 10.2210/pdb8pmz/pdb
• Descriptor: Pro-secreted protein ORF2, scFv_p61.15, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• Functional Keywords: hev, p domain, non-glycosylated, glycan-insensitive, neutralizing antibody (nab), viral protein
• Biological source: Paslahepevirus balayani; More
• Total number of polymer chains: 4
• Total formula weight: 100621.91

Authors

Ssebyatika, G.,Krey, T. (deposition date: 2023-06-29, release date: 2024-07-10)

• Primary citation: Ssebyatika, G.,Dinkelborg, K.,Stroeh, L.J.,Hinte, F.,Corneillie, L.,Hueffner, L.,Guzman, E.M.,Nankya, P.L.,Plueckebaum, N.,Prallet, S.,Mehnert, A.K.,Verhoye, L.,Juergens, C.,Steinmann, E.,Wedemeyer, H.,Viejo-Borbolla, A.,Dao Thi, L.V.,Pietschmann, T.,Luetgehetmann, M.,Meuleman, P.,Dandri, M.,Krey, T.,Behrendt, P.; A novel class of broadly neutralizing hepatitis E virus-specific human antibodies; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.912 Å)