7TDN

CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain

Summary for 7TDN

• Entry DOI: 10.2210/pdb7tdn/pdb
• EMDB information: 25835
• Descriptor: Claudin-4, Heat-labile enterotoxin B chain, COP-3 Fab Heavy chain, ... (4 entities in total)
• Functional Keywords: claudin, cell adhesion, enterotoxin, fab, antibody fragment, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 86220.54

Authors

Vecchio, A.J. (deposition date: 2022-01-01, release date: 2022-02-09, Last modification date: 2024-01-17)

• Primary citation: Orlando, B.J.,Dominik, P.K.,Roy, S.,Ogbu, C.P.,Erramilli, S.K.,Kossiakoff, A.A.,Vecchio, A.J.; Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.; J.Biol.Chem., 298:102357-102357, 2022; PubMed: 35952760; DOI: 10.1016/j.jbc.2022.102357

Experimental method