7TDN
CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Claudin-4 | polymer | 209 | 22090.2 | 1 | UniProt (O14493) Pfam (PF00822) | Homo sapiens (human) | Clostridium perfringens enterotoxin receptor,CPE-R,CPE-receptor,Williams-Beuren syndrome chromosomal region 8 protein |
| 2 | B (B) | Heat-labile enterotoxin B chain | polymer | 134 | 15114.9 | 1 | UniProt (P01558) | Clostridium perfringens | |
| 3 | C (H) | COP-3 Fab Heavy chain | polymer | 237 | 25286.1 | 1 | Homo sapiens (Human) | ||
| 4 | D (L) | COP-3 Fab Light chain | polymer | 217 | 23729.3 | 1 | Homo sapiens (Human) |
Sequence modifications
B: 192 - 319 (UniProt: P01558)
| PDB | External Database | Details |
|---|---|---|
| Met 191 | - | initiating methionine |
| Gly 320 | - | expression tag |
| Leu 321 | - | expression tag |
| Val 322 | - | expression tag |
| Pro 323 | - | expression tag |
| Arg 324 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86220.5 | |
| All* | Total formula weight | 86220.5 |
