8PMX
rat HEV P domain in complex with glycan-sensitive nAb p60.12
Summary for 8PMX
Entry DOI | 10.2210/pdb8pmx/pdb |
Descriptor | Pro-secreted protein ORF2, Fab p60.12-HC, Fab p60.12-LC (3 entities in total) |
Functional Keywords | rat hev, p domain, non-glycosylated, glycan-sensitive, neutralizing antibody (nab), viral protein |
Biological source | Hepatitis E virus rat/R63/DEU/2009 More |
Total number of polymer chains | 4 |
Total formula weight | 83725.76 |
Authors | |
Primary citation | Ssebyatika, G.,Dinkelborg, K.,Stroeh, L.J.,Hinte, F.,Corneillie, L.,Hueffner, L.,Guzman, E.M.,Nankya, P.L.,Plueckebaum, N.,Prallet, S.,Mehnert, A.K.,Verhoye, L.,Juergens, C.,Steinmann, E.,Wedemeyer, H.,Viejo-Borbolla, A.,Dao Thi, L.V.,Pietschmann, T.,Luetgehetmann, M.,Meuleman, P.,Dandri, M.,Krey, T.,Behrendt, P. A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.922 Å) |
Structure validation
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