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2HW8
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Structure of ribosomal protein L1-mRNA complex at 2.1 resolution.
Descriptor: 1,4-BUTANEDIOL, 36-MER, 50S ribosomal protein L1, ...
Authors:Tishchenko, S, Nikonova, E, Nikulin, A, Nevskaya, N, Volchkov, S, Piendl, W, Garber, M, Nikonov, S.
Deposit date:2006-08-01
Release date:2006-12-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the ribosomal protein L1-mRNA complex at 2.1 A resolution: common features of crystal packing of L1-RNA complexes.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2HW9
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Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWA
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Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWB
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A comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
Descriptor: 5-(3-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PROPYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-11-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWC
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-11-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWD
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor: 5-(3-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PROPYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-09-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWE
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-09-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWF
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor: 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE, HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 1A COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-09-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWG
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Structure of phosphorylated Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system
Descriptor: MAGNESIUM ION, OXALATE ION, Phosphoenolpyruvate-protein phosphotransferase
Authors:Lim, K, Teplyakov, A, Herzberg, O.
Deposit date:2006-08-01
Release date:2006-11-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HWH
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HCV NS5B allosteric inhibitor complex
Descriptor: 4-METHYL-N-{(5E)-5-[(5-METHYL-2-FURYL)METHYLENE]-4-OXO-4,5-DIHYDRO-1,3-THIAZOL-2-YL}BENZENESULFONAMIDE, RNA-directed RNA polymerase (NS5B) (p68)
Authors:Yao, N.
Deposit date:2006-08-01
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2HWI
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HCV NS5B allosteric inhibitor complex
Descriptor: (2S)-({(5Z)-5-[(5-ETHYL-2-FURYL)METHYLENE]-4-OXO-4,5-DIHYDRO-1,3-THIAZOL-2-YL}AMINO)(4-FLUOROPHENYL)ACETIC ACID, RNA-directed RNA polymerase (NS5B) (p68)
Authors:Yao, N.
Deposit date:2006-08-01
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2HWJ
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Crystal structure of protein Atu1540 from Agrobacterium tumefaciens
Descriptor: Hypothetical protein Atu1540
Authors:Chang, C, Xu, X, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-08-01
Release date:2006-08-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of protein Atu1540 from Agrobacterium tumefaciens
To be Published
2HWK
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Crystal Structure of Venezuelan Equine Encephalitis Alphavirus nsP2 Protease Domain
Descriptor: FORMIC ACID, helicase nsP2
Authors:Russo, A.T, White, M.A, Watowich, S.J.
Deposit date:2006-08-01
Release date:2006-09-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Crystal Structure of the Venezuelan Equine Encephalitis Alphavirus nsP2 Protease.
Structure, 14, 2006
2HWL
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BU of 2hwl by Molmil
Crystal structure of thrombin in complex with fibrinogen gamma' peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen gamma' peptide, Prothrombin, ...
Authors:Pineda, A.O, Chen, Z.W, Marino, F, Mathews, F.S, Mosesson, M.W, Di Cera, E.
Deposit date:2006-08-01
Release date:2006-09-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of thrombin in complex with fibrinogen gamma' peptide.
Biophys.Chem., 125, 2007
2HWM
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BU of 2hwm by Molmil
Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWN
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BU of 2hwn by Molmil
Crystal Structure of RII alpha Dimerization/Docking domain of PKA bound to the D-AKAP2 peptide
Descriptor: A Kinase binding peptide, GLYCEROL, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Kinderman, F, Kim, C.
Deposit date:2006-08-01
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase.
Mol.Cell, 24, 2006
2HWO
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BU of 2hwo by Molmil
Crystal structure of Src kinase domain in complex with covalent inhibitor
Descriptor: GLYCEROL, N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src
Authors:Rauh, D, Blair, J.A, Shokat, K.M.
Deposit date:2006-08-01
Release date:2007-02-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nat.Chem.Biol., 3, 2007
2HWP
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BU of 2hwp by Molmil
Crystal structure of Src kinase domain in complex with covalent inhibitor PD168393
Descriptor: N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src
Authors:Rauh, D, Blair, J.A, Shokat, K.M.
Deposit date:2006-08-01
Release date:2007-02-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nat.Chem.Biol., 3, 2007
2HWQ
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BU of 2hwq by Molmil
Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists
Descriptor: Peroxisome proliferator-activated receptor gamma, [(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-5-YL)OXY]ACETIC ACID
Authors:Peng, Y.H, Lu, I.L, Mahindroo, N, Lin, C.H, Hsieh, H.P, Wu, S.Y.
Deposit date:2006-08-01
Release date:2007-08-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2HWR
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BU of 2hwr by Molmil
Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists
Descriptor: 2-[(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-4-YL)OXY]-2-METHYLPROPANOIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Peng, Y.H, Lu, I.L, Mahindroo, N, Lin, C.H, Hsieh, H.P, Wu, S.Y.
Deposit date:2006-08-01
Release date:2007-08-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2HWT
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BU of 2hwt by Molmil
NMR solution structure of the Master-Rep protein nuclease domain (2-95) from the Faba Bean Necrotic Yellows Virus
Descriptor: Putative replicase-associated protein
Authors:Vega-Rocha, S, Gronenborn, B, Gronenborn, A.M, Campos-Olivas, R.
Deposit date:2006-08-02
Release date:2007-06-26
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution structure of the endonuclease domain from the master replication initiator protein of the nanovirus faba bean necrotic yellows virus and comparison with the corresponding geminivirus and circovirus structures
Biochemistry, 46, 2007
2HWU
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BU of 2hwu by Molmil
Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with uridine and phosphate ion at 2.91A resolution
Descriptor: PHOSPHATE ION, URIDINE, Uridine phosphorylase
Authors:Timofeev, V.I, Gabdulkhakov, A.G, Dontsova, M.V, Mikhailov, A.M.
Deposit date:2006-08-02
Release date:2007-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with uridine and phosphate ion at 2.91A resolution
To be Published
2HWV
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BU of 2hwv by Molmil
Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily.
Descriptor: DNA-binding response regulator VicR, SULFATE ION
Authors:Trinh, C.H, Liu, Y, Phillips, S.E.V, Phillips-Jones, M.K.
Deposit date:2006-08-02
Release date:2007-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the response regulator VicR DNA-binding domain.
Acta Crystallogr.,Sect.D, 63, 2007
2HWW
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BU of 2hww by Molmil
Structure of PIN domain of human SMG6
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
2HWX
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BU of 2hwx by Molmil
Structure of human SMG6 E1282C PIN domain mutant.
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006

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