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2HWQ

Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists

Summary for 2HWQ
Entry DOI10.2210/pdb2hwq/pdb
Related2hwr
DescriptorPeroxisome proliferator-activated receptor gamma, [(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-5-YL)OXY]ACETIC ACID (3 entities in total)
Functional Keywordsppar, ligand binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P37231
Total number of polymer chains2
Total formula weight62515.65
Authors
Peng, Y.H.,Lu, I.L.,Mahindroo, N.,Lin, C.H.,Hsieh, H.P.,Wu, S.Y. (deposition date: 2006-08-01, release date: 2007-08-07, Last modification date: 2023-10-25)
Primary citationMahindroo, N.,Peng, Y.H.,Lin, C.H.,Tan, U.K.,Prakash, E.,Lien, T.W.,Lu, I.L.,Lee, H.J.,Hsu, J.T.A.,Chen, X.,Liao, C.C.,Lyu, P.C.,Chao, Y.S.,Wu, S.Y.,Hsieh, H.P.
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49:6421-6424, 2006
Cited by
PubMed: 17034149
DOI: 10.1021/jm060663c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

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