2HWX
Structure of human SMG6 E1282C PIN domain mutant.
Summary for 2HWX
Entry DOI | 10.2210/pdb2hwx/pdb |
Related | 2HWW |
Descriptor | Telomerase-binding protein EST1A (2 entities in total) |
Functional Keywords | rna degradation, decay, nmd, est1a, p bodies, rna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleolus: Q86US8 |
Total number of polymer chains | 1 |
Total formula weight | 20566.73 |
Authors | Glavan, F.,Behm-Ansmant, I.,Izaurralde, E.,Conti, E. (deposition date: 2006-08-02, release date: 2006-11-14, Last modification date: 2024-02-14) |
Primary citation | Glavan, F.,Behm-Ansmant, I.,Izaurralde, E.,Conti, E. Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. Embo J., 25:5117-5125, 2006 Cited by PubMed: 17053788DOI: 10.1038/sj.emboj.7601377 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)