2HWW

Structure of PIN domain of human SMG6

Summary for 2HWW

Entry DOI	10.2210/pdb2hww/pdb
Descriptor	Telomerase-binding protein EST1A (2 entities in total)
Functional Keywords	degradation, decay, nmd, est1a, p bodies, rna binding protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus, nucleolus: Q86US8
Total number of polymer chains	3
Total formula weight	61778.10
Authors	Glavan, F.,Behm-Ansmant, I.,Izaurralde, E.,Conti, E. (deposition date: 2006-08-02, release date: 2006-11-14, Last modification date: 2023-08-30)
Primary citation	Glavan, F.,Behm-Ansmant, I.,Izaurralde, E.,Conti, E. Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. Embo J., 25:5117-5125, 2006 Cited by PubMed: 17053788 DOI: 10.1038/sj.emboj.7601377 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation