2HWB
A comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
Summary for 2HWB
Entry DOI | 10.2210/pdb2hwb/pdb |
Descriptor | HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ... (5 entities in total) |
Functional Keywords | rhinovirus coat protein, icosahedral virus, virus |
Biological source | Human rhinovirus 14 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303 |
Total number of polymer chains | 4 |
Total formula weight | 94823.72 |
Authors | Kim, K.H.,Rossmann, M.G. (deposition date: 1994-01-25, release date: 1994-11-01, Last modification date: 2024-05-29) |
Primary citation | Kim, K.H.,Willingmann, P.,Gong, Z.X.,Kremer, M.J.,Chapman, M.S.,Minor, I.,Oliveira, M.A.,Rossmann, M.G.,Andries, K.,Diana, G.D.,Dutko, F.J.,McKinlay, M.A.,Pevear, D.C. A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A. J.Mol.Biol., 230:206-227, 1993 Cited by PubMed: 8383771DOI: 10.1006/jmbi.1993.1137 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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