PDB: 225946 件ウェブページステータス検索Chemie searchBIRD

---

4XJL	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a HTS lead compound 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, DI(HYDROXYETHYL)ETHER, N-(1,2,3-benzothiadiazol-5-yl)-4-phenylpiperazine-1-carboxamide, ... 著者 Finzel, B.C, Dai, R. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Fragment based inhibitor design of Mycobacterium tuberculosis BioA (http://hdl.handle.net/11299/171084) Thesis, University Of Minnesota, 2015
4XJM	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a HTS lead compound 分子名称: 3-{1-[(5-acetylthiophen-2-yl)carbonyl]piperidin-4-yl}-N-(3-methoxyphenyl)propanamide, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Finzel, B.C, Dai, R. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fragment based inhibitor design of Mycobacterium tuberculosis BioA (http://hdl.handle.net/11299/171084) Thesis, University of Minnesota, 2015
6O9F	The structure of Thermomyces Lanuginosa lipase in complex with 1,3 diacylglycerol in a monoclinic crystal form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate, CALCIUM ION, ... 著者 McPherson, A. 登録日 2019-03-13 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 The Crystal Structures of Thermomyces (Humicola) Lanuginosa Lipase in Complex with Enzymatic Reactants Curr Enzym Inhib, 16, 2020
6OSZ	High Resolution Structure of the Monoclinic Form of Thermomyces Lanuginosa Lipase Complexed with Its Catalytic Products 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate, CALCIUM ION, ... 著者 McPherson, A. 登録日 2019-05-02 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 The Crystal Structures of Thermomyces (Humicola) Lanuginosa Lipase in Complex with Enzymatic Reactants Curr Enzym Inhib, 16, 2020
6O8V	The structure of lipase from Thermomyces Lanuginosa in complex with 1,3 diacylglycerol: Rhombohedral crystal form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate, Lipase, ... 著者 McPherson, A. 登録日 2019-03-12 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The Crystal Structures of Thermomyces (Humicola) Lanuginosa Lipase in Complex with Enzymatic Reactants Curr Enzym Inhib, 16, 2020
4WA2	The crystal structure of hemagglutinin from a H3N8 influenza virus isolated from New England harbor seals in complex with 3'SLN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Yang, H, Villanueva, J.M, Gubareva, L.V, Stevens, J. 登録日 2014-08-28 公開日 2015-01-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89, 2015
6U60	Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ... 著者 Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-08-28 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
4LV2	AmpC beta-lactamase in complex with [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4LV3	AmpC beta-lactamase in complex with (3,5-di-tert-butylphenyl) boronic acid 分子名称: (3,5-di-tert-butylphenyl)boronic acid, Beta-lactamase, PHOSPHATE ION 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4LV1	AmpC beta-lactamase in complex with [1-(3-chlorophenyl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(3-chlorophenyl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
6CXD	Crystal structure of peptidase B from Yersinia pestis CO92 at 2.75 A resolution 分子名称: Peptidase B, SULFATE ION 著者 Woinska, M, Lipowska, J, Shabalin, I.G, Cymborowski, M, Grimshaw, S, Winsor, J, Shuvalova, L, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-04-02 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
4M8M	Crystal structure of the active dimer of zebrafish PlexinC1 cytoplasmic region 分子名称: GCN4 coiled-coil fused zebrafish PlexinC1 著者 Wang, Y, Pascoe, H.G, Zhang, X. 登録日 2013-08-13 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.307 Å) 主引用文献 Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin. Elife, 2, 2013
4MEX	Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2014-06-25 実験手法 X-RAY DIFFRACTION (3.902 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
6RUQ	Structure of GluA2cryst in complex the antagonist ZK200775 and the negative allosteric modulator GYKI53655 at 4.65 A resolution 分子名称: (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Krintel, C, Venskutonyte, R, Mirza, O.A, Gajhede, M, Kastrup, J.S. 登録日 2019-05-28 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.65 Å) 主引用文献 Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. Febs J., 288, 2021
5V0S	Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis 分子名称: CALCIUM ION, Prephenate dehydrogenase, SULFATE ION 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-28 公開日 2017-03-08 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
5UYY	Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine 分子名称: Prephenate dehydrogenase, TYROSINE 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-24 公開日 2017-03-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
7ZKX	SRPK2 IN COMPLEX WITH INHIBITOR 分子名称: 1,2-ETHANEDIOL, ACETATE ION, N-[3-[[[2-(6-chloranyl-5-fluoranyl-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-N-methyl-methanesulfonamide, ... 著者 Graedler, U. 登録日 2022-04-13 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core. J.Med.Chem., 66, 2023
5KJR	Crystal structure of the ADCC-potent antibody N60-i3 Fab in complex with HIV-1 Clade A/E gp120 W69A/S115W mutant and M48U1. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, M48U1 CD4 MIMETIC PEPTIDE, ... 著者 Tolbert, W.D, Pazgier, M. 登録日 2016-06-20 公開日 2016-07-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability. J.Virol., 90, 2016
6TV1	ATPase domain D3 of the EssC coupling protein from S. aureus USA300 分子名称: EssC protein, GLYCEROL 著者 Mietrach, N.A, Geibel, S. 登録日 2020-01-08 公開日 2020-01-29 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Substrate Interaction with the EssC Coupling Protein of the Type VIIb Secretion System. J.Bacteriol., 202, 2020
6VRS	Single particle reconstruction of glucose isomerase from Streptomyces rubiginosus based on data acquired in the presence of substantial aberrations 分子名称: MANGANESE (II) ION, xylose isomerase 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-09 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
6VSC	Single particle reconstruction of HemQ from Geobacillus based on data acquired in the presence of substantial aberrations 分子名称: HemQ 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-11 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
6VSA	Single particle reconstruction of HemQ from Geobacillus based on data acquired in the presence of substantial aberrations 分子名称: HemQ 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-10 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.32 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
4NM5	Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 c-motif 分子名称: ADENOSINE-5'-DIPHOSPHATE, Axin-1, CHLORIDE ION, ... 著者 Stamos, J.L, Chu, M.L.-H, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-11-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
4NM7	Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 e-motif 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE-5'-DIPHOSPHATE, Axin-1, ... 著者 Stamos, J.L, Chu, M.L.-H, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-11-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
7SAU	Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Schleiferia thermophila 分子名称: GldM, Gliding motility protein GldL 著者 Hennell James, R, Deme, J.C, Lea, S.M. 登録日 2021-09-23 公開日 2022-03-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes. Mbio, 13, 2022

 

12345678910111213141516>