5UYY

Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine

Summary for 5UYY

Entry DOI	10.2210/pdb5uyy/pdb
Related	5USC
Descriptor	Prephenate dehydrogenase, TYROSINE (3 entities in total)
Functional Keywords	prephenate dehydrogenase, tyra, bacillus anthracis, csgid, structural genomics, center for structural genomics of infectious diseases, oxidoreductase
Biological source	Bacillus anthracis
Total number of polymer chains	4
Total formula weight	171555.85
Authors	Shabalin, I.G.,Hou, J.,Cymborowski, M.T.,Kwon, K.,Christendat, D.,Gritsunov, A.O.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-24, release date: 2017-03-08, Last modification date: 2023-10-04)
Primary citation	Shabalin, I.G.,Gritsunov, A.,Hou, J.,Slawek, J.,Miks, C.D.,Cooper, D.R.,Minor, W.,Christendat, D. Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287:2235-2255, 2020 Cited by PubMed: 31750992 DOI: 10.1111/febs.15150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation