5V0S

Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis

Summary for 5V0S

• Entry DOI: 10.2210/pdb5v0s/pdb
• Related: 5USC 5UYY
• Descriptor: Prephenate dehydrogenase, SULFATE ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: prephenate dehydrogenase, tyra, bacillus anthracis, csgid, structural genomics, center for structural genomics of infectious diseases, oxidoreductase
• Biological source: Bacillus anthracis
• Total number of polymer chains: 2
• Total formula weight: 16034.08

Authors

Shabalin, I.G.,Hou, J.,Cymborowski, M.T.,Otwinowski, Z.,Kwon, K.,Christendat, D.,Gritsunov, A.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-28, release date: 2017-03-08, Last modification date: 2022-03-23)

• Primary citation: Shabalin, I.G.,Gritsunov, A.,Hou, J.,Slawek, J.,Miks, C.D.,Cooper, D.R.,Minor, W.,Christendat, D.; Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.; Febs J., 287:2235-2255, 2020; PubMed: 31750992; DOI: 10.1111/febs.15150

Experimental method

X-RAY DIFFRACTION (2.01 Å)