6U60
Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine
Replaces: 5USCSummary for 6U60
Entry DOI | 10.2210/pdb6u60/pdb |
Descriptor | Prephenate dehydrogenase, TYROSINE, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase |
Biological source | Bacillus anthracis |
Total number of polymer chains | 2 |
Total formula weight | 86631.29 |
Authors | Shabalin, I.G.,Hou, J.,Kutner, J.,Grimshaw, S.,Christendat, D.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2019-08-28, release date: 2019-09-11, Last modification date: 2023-10-11) |
Primary citation | Shabalin, I.G.,Gritsunov, A.,Hou, J.,Slawek, J.,Miks, C.D.,Cooper, D.R.,Minor, W.,Christendat, D. Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287:2235-2255, 2020 Cited by PubMed: 31750992DOI: 10.1111/febs.15150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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