1B47
| STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70 | 分子名称: | CALCIUM ION, CBL | 著者 | Meng, W, Sawasdikosol, S, Burakoff, S.J, Eck, M.J. | 登録日 | 1999-01-06 | 公開日 | 1999-04-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398, 1999
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2CBL
| N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70 | 分子名称: | CALCIUM ION, PROTO-ONCOGENE CBL, ZAP-70 | 著者 | Meng, W, Sawasdikosol, S, Burakoff, S.J, Eck, M.J. | 登録日 | 1998-08-28 | 公開日 | 1999-05-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398, 1999
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1FBV
| STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES | 分子名称: | SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... | 著者 | Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 2000-07-17 | 公開日 | 2000-08-30 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell(Cambridge,Mass.), 102, 2000
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1YVH
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3BUX
| Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met | 分子名称: | 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL | 著者 | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | 登録日 | 2008-01-03 | 公開日 | 2008-02-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUM
| Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2 | 分子名称: | E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2 | 著者 | Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J. | 登録日 | 2008-01-03 | 公開日 | 2008-02-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUW
| Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk | 分子名称: | 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL | 著者 | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | 登録日 | 2008-01-03 | 公開日 | 2008-02-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUN
| Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4 | 分子名称: | 13-meric peptide from Protein sprouty homolog 4, E3 ubiquitin-protein ligase CBL | 著者 | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | 登録日 | 2008-01-03 | 公開日 | 2008-02-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3BUO
| Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor' | 分子名称: | 13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL | 著者 | Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. | 登録日 | 2008-01-03 | 公開日 | 2008-02-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
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3OB1
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3OB2
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3OP0
| Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide | 分子名称: | Epidermal growth factor receptor, NICKEL (II) ION, SODIUM ION, ... | 著者 | Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Ugochukwu, E, Muniz, J.R.C, Vollmar, M, Canning, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-08-31 | 公開日 | 2010-10-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide To be Published
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3PLF
| Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain | 分子名称: | CALCIUM ION, CHLORIDE ION, E3 ubiquitin-protein ligase CBL, ... | 著者 | Sun, Q, Sivaraman, J. | 登録日 | 2010-11-15 | 公開日 | 2010-12-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding Febs Lett., 585, 2011
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3PFV
| Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide | 分子名称: | 1,2-ETHANEDIOL, 11-meric peptide from Epidermal growth factor receptor, CHLORIDE ION, ... | 著者 | Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Muniz, J.R.C, Vollmar, M, Canning, P, Gileadi, O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-10-29 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide To be Published
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3VGO
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2Y1N
| Structure of c-Cbl-ZAP-70 peptide complex | 分子名称: | CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, ... | 著者 | Dou, H, Sibbet, G.J, Huang, D.T. | 登録日 | 2010-12-08 | 公開日 | 2012-01-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19, 2012
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2Y1M
| Structure of native c-Cbl | 分子名称: | CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION | 著者 | Dou, H, Sibbet, G.J, Huang, D.T. | 登録日 | 2010-12-08 | 公開日 | 2012-01-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19, 2012
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4A4C
| Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex | 分子名称: | CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ... | 著者 | Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T. | 登録日 | 2011-10-08 | 公開日 | 2012-01-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl Nat.Struct.Mol.Biol., 19, 2012
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4A4B
| Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex | 分子名称: | CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ... | 著者 | Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T. | 登録日 | 2011-10-08 | 公開日 | 2012-01-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | 主引用文献 | Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl Nat.Struct.Mol.Biol., 19, 2012
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3VRN
| Crystal structure of the tyrosine kinase binding domain of Cbl-c | 分子名称: | CALCIUM ION, Signal transduction protein CBL-C | 著者 | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | 登録日 | 2012-04-13 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c J.Biochem., 152, 2012
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3VRR
| Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant) in complex with phospho-EGFR peptide | 分子名称: | CALCIUM ION, Epidermal growth factor receptor, Signal transduction protein CBL-C | 著者 | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | 登録日 | 2012-04-13 | 公開日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
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3VRQ
| Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant) | 分子名称: | CALCIUM ION, Signal transduction protein CBL-C | 著者 | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | 登録日 | 2012-04-13 | 公開日 | 2013-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
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3VRO
| Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-Src peptide | 分子名称: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase Src, Signal transduction protein CBL-C | 著者 | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | 登録日 | 2012-04-13 | 公開日 | 2013-03-06 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
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3VRP
| Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-EGFR peptide | 分子名称: | CALCIUM ION, Epidermal growth factor receptor, Signal transduction protein CBL-C | 著者 | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | 登録日 | 2012-04-13 | 公開日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
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3ZNI
| Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ... | 著者 | Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. | 登録日 | 2013-02-14 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3. Nat.Struct.Mol.Biol., 20, 2013
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