3VGO

Crystal structure of the N-terminal fragment of Cbl-b

Summary for 3VGO

Entry DOI	10.2210/pdb3vgo/pdb
Descriptor	E3 ubiquitin-protein ligase CBL-B (1 entity in total)
Functional Keywords	merohedral twinning, e3 ligase, ligase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q13191
Total number of polymer chains	3
Total formula weight	136914.89
Authors	Kobashigawa, Y.,Noda, N.N.,Inagaki, F. (deposition date: 2011-08-18, release date: 2011-12-14, Last modification date: 2023-11-08)
Primary citation	Kobashigawa, Y.,Tomitaka, A.,Kumeta, H.,Noda, N.N.,Yamaguchi, M.,Inagaki, F. Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108:20579-20584, 2011 Cited by PubMed: 22158902 DOI: 10.1073/pnas.1110712108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation