3VGO
Crystal structure of the N-terminal fragment of Cbl-b
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001784 | molecular_function | phosphotyrosine residue binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
| A | 0023051 | biological_process | regulation of signaling |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0001784 | molecular_function | phosphotyrosine residue binding |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0007166 | biological_process | cell surface receptor signaling pathway |
| B | 0023051 | biological_process | regulation of signaling |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0001784 | molecular_function | phosphotyrosine residue binding |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0007166 | biological_process | cell surface receptor signaling pathway |
| C | 0023051 | biological_process | regulation of signaling |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHlMCtsCL |
| Chain | Residue | Details |
| A | CYS388-LEU397 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 216 |
| Details | Region: {"description":"EF-hand-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P22681","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC/PRKCQ","evidences":[{"source":"PubMed","id":"19549985","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"20525694","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
