PDB: 322 件ウェブページステータス検索Chemie searchBIRD

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9CJA	Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure 分子名称: ZINC ION, Zinc finger protein 711 著者 Rua, A.J, Alexandrescu, A.T. 登録日 2024-07-05 公開日 2024-07-17 最終更新日 2024-10-09 実験手法 SOLUTION NMR 主引用文献 Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure. Protein Sci., 33, 2024
5WJQ	mouseZFP568-ZnF2-11 in complex with DNA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ... 著者 Patel, A, Cheng, X. 登録日 2017-07-24 公開日 2018-03-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.794 Å) 主引用文献 DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell, 173, 2018
4IS1	Crystal structure of ZNF217 bound to DNA 分子名称: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... 著者 Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. 登録日 2013-01-16 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. J.Biol.Chem., 288, 2013
8H9H	Crystal structure of ZBTB7A in complex with GACCC-containing sequence 分子名称: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ... 著者 Yang, Y. 登録日 2022-10-25 公開日 2023-04-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4. Febs J., 290, 2023
5N14	NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain 分子名称: Protein (chimeric oligourea-peptide zinc finger), ZINC ION 著者 Venkateshaiah M, V.K, Salgado, G. 登録日 2017-02-05 公開日 2017-04-12 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain. To Be Published
6KI6	Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region 分子名称: B-cell lymphoma/leukemia 11A, DNA (5'-D(*AP*TP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*A)-3'), ... 著者 Li, F.D, Yang, Y, Shi, Y.Y. 登録日 2019-07-17 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the recognition of gamma-globin gene promoter by BCL11A. Cell Res., 29, 2019
9AZI	NMR solution structure of cell-permeant miniature protein ZF5.3 分子名称: Designed Zinc finger protein 5.3, ZINC ION 著者 Giudice, J.A, Kelly, M, Schepartz, A. 登録日 2024-03-11 公開日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and mechanistic basis for efficient endosomal escape by designed mini-proteins To be published
7EYI	Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation 分子名称: BORIC ACID, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... 著者 Yang, Y, Shi, Y.Y. 登録日 2021-05-31 公開日 2021-09-01 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
4M9E	Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA 分子名称: ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... 著者 Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. 登録日 2013-08-14 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42, 2014
8CUC	Crystal structure analysis of SALL4 zinc finger domain in complex with DNA 分子名称: DNA (5'-D(P*CP*GP*AP*AP*AP*TP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*AP*AP*TP*AP*TP*TP*TP*CP*G)-3'), Sal-like protein 4, ... 著者 Seo, H.S, Dhe-Paganon, S. 登録日 2022-05-17 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal Structure Analysis of SALL4 Zinc Finger domain in complex with DNA To Be Published
4M9V	Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X. 登録日 2013-08-15 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.969 Å) 主引用文献 DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom. Biochemistry, 52, 2013
8JPY	Solution NMR Structure of Zinc-fingers 1 and 2 (fragment 257-320) from human Insulinoma-associated protein 1(INSM1) 分子名称: Insulinoma-associated protein 1, ZINC ION 著者 He, X.L, Yang, Y.H. 登録日 2023-06-13 公開日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Zinc-fingers 1 and 2 (fragment 257-320) from human Insulinoma-associated protein 1(INSM1) To Be Published
8JQ1	Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1) 分子名称: Insulinoma-associated protein 1, ZINC ION 著者 He, X.L, Yang, Y.H. 登録日 2023-06-13 公開日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1) To Be Published
4GZN	Mouse ZFP57 zinc fingers in complex with methylated DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Liu, Y, Zhang, X, Cheng, X. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev., 26, 2012
4F2J	Crystal structure of ZNF217 bound to DNA, P6522 crystal form 分子名称: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', ZINC ION, Zinc finger protein 217 著者 Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. 登録日 2012-05-08 公開日 2013-02-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217 J.Biol.Chem., 288, 2013
6U9Q	Crystal Structure Analysis of DNA-BCL11A Znf domain complex 分子名称: B-cell lymphoma/leukemia 11A, DNA3, DNA5, ... 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2019-09-09 公開日 2020-09-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal Structure Analysis of TAF1 Bromodomain To Be Published
5EH2	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III 分子名称: DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-27 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
5EI9	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence I 分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*GP*A)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-29 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.921 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
5EGB	Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence II 分子名称: DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... 著者 Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. 登録日 2015-10-26 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.977 Å) 主引用文献 Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30, 2016
4X9J	EGR-1 with Doubly Methylated DNA 分子名称: DNA (5'-D(*AP*GP*(5CM)P*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*(5CM)P*GP*C)-3'), Early growth response protein 1, ... 著者 White, M.A, Zandarashvili, L, Iwahara, J. 登録日 2014-12-11 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.412 Å) 主引用文献 Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1. Febs Lett., 589, 2015
6UCO	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: BTD in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-09-17 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
6UCP	Zinc finger 2 from the transcription factor Sp1 DNA binding domain 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-09-17 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
1JK2	Zif268 D20A mutant bound to the GCT DNA site 分子名称: 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... 著者 Miller, J.C, Pabo, C.O. 登録日 2001-07-11 公開日 2001-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. J.Mol.Biol., 313, 2001
7TXC	HIC2 zinc finger domain in complex with the DNA binding motif-2 of the BCL11A enhancer 分子名称: DNA (5'-D(*AP*CP*TP*GP*TP*TP*GP*GP*CP*AP*TP*TP*AP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*TP*AP*AP*TP*GP*CP*CP*AP*AP*CP*AP*GP*T)-3'), Hypermethylated in cancer 2 protein, ... 著者 Horton, J.R, Ren, R, Cheng, X. 登録日 2022-02-08 公開日 2022-06-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nat.Genet., 54, 2022
1G2F	STRUCTURE OF A CYS2HIS2 ZINC FINGER/TATA BOX COMPLEX (TATAZF;CLONE #6) 分子名称: 5'-D(*GP*AP*CP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*AP*G)-3', 5'-D(*TP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*GP*TP*CP*C)-3', TATA BOX ZINC FINGER PROTEIN, ... 著者 Wolfe, S.A, Grant, R.A, Elrod-Erickson, M, Pabo, C.O. 登録日 2000-10-18 公開日 2001-09-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes. Structure, 9, 2001

 

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