5EI9
Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence I
Summary for 5EI9
Entry DOI | 10.2210/pdb5ei9/pdb |
Related | 5EGB 5EH2 |
Descriptor | DNA (5'-D(*AP*TP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*C)-3'), Histone-lysine N-methyltransferase PRDM9, DNA (5'-D(*TP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*GP*A)-3'), ... (5 entities in total) |
Functional Keywords | protein-dna complex, recombination, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 60266.58 |
Authors | Patel, A.,Horton, J.R.,Wilson, G.G.,Zhang, X.,Cheng, X. (deposition date: 2015-10-29, release date: 2016-02-17, Last modification date: 2024-03-06) |
Primary citation | Patel, A.,Horton, J.R.,Wilson, G.G.,Zhang, X.,Cheng, X. Structural basis for human PRDM9 action at recombination hot spots. Genes Dev., 30:257-265, 2016 Cited by PubMed: 26833727DOI: 10.1101/gad.274928.115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.921 Å) |
Structure validation
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