7EYI

Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation

Summary for 7EYI

• Entry DOI: 10.2210/pdb7eyi/pdb
• Descriptor: Zinc finger and BTB domain-containing protein 7A, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... (6 entities in total)
• Functional Keywords: zbtb7a, gamma-globin, -200 cluste., structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 52876.80

Authors

Yang, Y.,Shi, Y.Y. (deposition date: 2021-05-31, release date: 2021-09-01, Last modification date: 2021-10-20)

• Primary citation: Yang, Y.,Ren, R.,Ly, L.C.,Horton, J.R.,Li, F.,Quinlan, K.G.R.,Crossley, M.,Shi, Y.,Cheng, X.; Structural basis for human ZBTB7A action at the fetal globin promoter.; Cell Rep, 36:109759-109759, 2021; PubMed: 34592153; DOI: 10.1016/j.celrep.2021.109759

Experimental method

X-RAY DIFFRACTION (2.401 Å)