7EYI
Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (G, H) | Zinc finger and BTB domain-containing protein 7A | polymer | 130 | 15111.7 | 2 | UniProt (O95365) Pfam (PF00096) | Homo sapiens (Human) | Factor binding IST protein 1,FBI-1,Factor that binds to inducer of short transcripts protein 1,HIV-1 1st-binding protein 1,Leukemia/lymphoma-related factor,POZ and Krueppel erythroid myeloid ontogenic factor,POK erythroid myeloid ontogenic factor,Pokemon,Pokemon 1,TTF-I-interacting peptide 21,TIP21,Zinc finger protein 857A |
| 2 | C, E (A, C) | DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3') | polymer | 18 | 5421.5 | 2 | Homo sapiens | ||
| 3 | D, F (B, D) | DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3') | polymer | 18 | 5612.6 | 2 | Homo sapiens | ||
| 4 | G, H, I, J, K... (G, H) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | O (B) | BORIC ACID | non-polymer | 61.8 | 1 | Chemie (BO3) | |||
| 6 | P, Q, R, S, T... (G, H, A, B, C...) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
G, H: 382 - 506 (UniProt: O95365)
| PDB | External Database | Details |
|---|---|---|
| Gly 378 | - | expression tag |
| Ser 379 | - | expression tag |
| His 380 | - | expression tag |
| Met 381 | - | expression tag |
| Trp 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 52291.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 585.1 | |
| All* | Total formula weight | 52876.8 |
