4M9E
Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA
Summary for 4M9E
Entry DOI | 10.2210/pdb4m9e/pdb |
Descriptor | Krueppel-like factor 4, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... (7 entities in total) |
Functional Keywords | dna methylation, transcription factor, cellular reprogramming, c2h2 zinc finger, dna binding, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus: Q60793 |
Total number of polymer chains | 3 |
Total formula weight | 16896.21 |
Authors | Liu, Y.,Olanrewaju, Y.O.,Blumenthal, R.M.,Zhang, X.,Cheng, X. (deposition date: 2013-08-14, release date: 2014-02-12, Last modification date: 2023-09-20) |
Primary citation | Liu, Y.,Olanrewaju, Y.O.,Zheng, Y.,Hashimoto, H.,Blumenthal, R.M.,Zhang, X.,Cheng, X. Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42:4859-4867, 2014 Cited by PubMed: 24520114DOI: 10.1093/nar/gku134 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.851 Å) |
Structure validation
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