4IS1

Crystal structure of ZNF217 bound to DNA

Summary for 4IS1

• Entry DOI: 10.2210/pdb4is1/pdb
• Related: 4F2J
• Descriptor: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', Zinc finger protein 217, ... (6 entities in total)
• Functional Keywords: zinc finger, transcription factor, metal binding protein-dna complex, metal binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 26522.16

Authors

Vandevenne, M.S.,Jacques, D.A.,Guss, J.M.,Mackay, J.P. (deposition date: 2013-01-16, release date: 2013-02-27, Last modification date: 2023-11-08)

• Primary citation: Vandevenne, M.,Jacques, D.A.,Artuz, C.,Nguyen, C.D.,Kwan, A.H.,Segal, D.J.,Matthews, J.M.,Crossley, M.,Guss, J.M.,Mackay, J.P.; New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217.; J.Biol.Chem., 288:10616-10627, 2013; PubMed: 23436653; DOI: 10.1074/jbc.M112.441451

Experimental method

X-RAY DIFFRACTION (2.1 Å)