5EH2

Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III

Summary for 5EH2

• Entry DOI: 10.2210/pdb5eh2/pdb
• Related: 5EGB 5EI9
• Descriptor: DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... (5 entities in total)
• Functional Keywords: protein-dna complex, recombination, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 60266.57

Authors

Patel, A.,Horton, J.R.,Wilson, G.G.,Zhang, X.,Cheng, X. (deposition date: 2015-10-27, release date: 2016-02-17, Last modification date: 2024-03-06)

• Primary citation: Patel, A.,Horton, J.R.,Wilson, G.G.,Zhang, X.,Cheng, X.; Structural basis for human PRDM9 action at recombination hot spots.; Genes Dev., 30:257-265, 2016; PubMed: 26833727; DOI: 10.1101/gad.274928.115

Experimental method

X-RAY DIFFRACTION (2.05 Å)