8OVD
| Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis | 分子名称: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | 著者 | Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M. | 登録日 | 2023-04-25 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex. Nat Commun, 15, 2024
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8OVC
| Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis | 分子名称: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | 著者 | Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M. | 登録日 | 2023-04-25 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex. Nat Commun, 15, 2024
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8K33
| SOD1 and Nanobody1 complex | 分子名称: | NB1, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Cheng, S. | 登録日 | 2023-07-14 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | SOD1 and Nanobody1 complex To Be Published
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8K3A
| SOD1 and Nanobody2 complex | 分子名称: | NB2, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Cheng, S. | 登録日 | 2023-07-14 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | SOD1 and Nanobody1 complex To Be Published
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8K3L
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8JD8
| Crystal structure of Citrus limon Cu-Zn superoxide dismutase | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T. | 登録日 | 2023-05-12 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon. Acta Crystallogr.,Sect.F, 79, 2023
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8CCX
| Human SOD1 in complex with S-XL6 cross-linker | 分子名称: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | 登録日 | 2023-01-27 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
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8Q6M
| Human SOD1 low dose data collecton | 分子名称: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | 登録日 | 2023-08-14 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
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7XX3
| Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) | 分子名称: | (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Padmanabhan, B, Unni, S. | 登録日 | 2022-05-28 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS) To Be Published
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7YPR
| Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | 分子名称: | COPPER (II) ION, POTASSIUM ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | 登録日 | 2022-08-04 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023
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8IQ1
| Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C. | 登録日 | 2023-03-15 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme. Cell Rep, 42, 2023
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8IQ0
| Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C. | 登録日 | 2023-03-15 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme. Cell Rep, 42, 2023
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7YPP
| Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | 分子名称: | CALCIUM ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | 登録日 | 2022-08-04 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023
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8GSQ
| Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. | 分子名称: | (9~{R})-3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-9-oxidanyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | 著者 | Aouti, S, Padmanabhan, B. | 登録日 | 2022-09-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based discovery of an antipsychotic drug, paliperidone, as a modulator of human superoxide dismutase 1: a potential therapeutic target in amyotrophic lateral sclerosis. Acta Crystallogr D Struct Biol, 79, 2023
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7WWY
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7WWT
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7WX0
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7WX1
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7T8F
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7T8E
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7T8H
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7T8G
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7FB6
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7FB9
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7NXX
| Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. | 登録日 | 2021-03-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
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