7T8E
G93A mutant of human SOD1 in P21 space group
Summary for 7T8E
Entry DOI | 10.2210/pdb7t8e/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, ACETATE ION, ... (5 entities in total) |
Functional Keywords | sod1, als, drug discovery, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 32195.98 |
Authors | Amporndanai, K.,Hasnain, S.S. (deposition date: 2021-12-16, release date: 2023-01-25, Last modification date: 2024-06-05) |
Primary citation | Watanabe, S.,Amporndanai, K.,Awais, R.,Latham, C.,Awais, M.,O'Neill, P.M.,Yamanaka, K.,Hasnain, S.S. Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement. Sci Rep, 14:12118-12118, 2024 Cited by PubMed: 38802492DOI: 10.1038/s41598-024-62903-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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