7T8H
G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group
Summary for 7T8H
Entry DOI | 10.2210/pdb7t8h/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, ACETATE ION, ... (6 entities in total) |
Functional Keywords | sod1, als, drug discovery, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 32838.44 |
Authors | Amporndanai, K.,Hasnain, S.S. (deposition date: 2021-12-16, release date: 2023-01-25, Last modification date: 2023-10-25) |
Primary citation | Amporndanai, K.,Watanabe, S.,Awais, R.,Latham, C.,O Neill, P.M.,Yamanaka, K.,Hasnain, S.S. Disease Onset and its course are delayed by on-target Cellular SOD1 Engagement of Organo-selenium drug compounds for Amyotrophic Lateral Sclerosis To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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