7XX3
Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)
Summary for 7XX3
Entry DOI | 10.2210/pdb7xx3/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | superoxide dismutase, protein aggregation, modulator, toxic trimer, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 10 |
Total formula weight | 192834.62 |
Authors | |
Primary citation | Unni, S.,Padmanabhan, B. Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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