7XX3

Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)

Summary for 7XX3

• Entry DOI: 10.2210/pdb7xx3/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: superoxide dismutase, protein aggregation, modulator, toxic trimer, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 10
• Total formula weight: 192834.62

Authors

Padmanabhan, B.,Unni, S. (deposition date: 2022-05-28, release date: 2023-12-13)

• Primary citation: Unni, S.,Padmanabhan, B.; Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)