7WX1
E40K/M117L variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)
Summary for 7WX1
Entry DOI | 10.2210/pdb7wx1/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, COPPER (II) ION, ... (4 entities in total) |
Functional Keywords | superoxide dismutase, sod, sod1, oxidoreductase e40km117l, metal binding protein |
Biological source | Canis lupus familiaris (dog) |
Total number of polymer chains | 2 |
Total formula weight | 31951.38 |
Authors | Narikiyo, S.,Furukawa, Y.,Akutsu, M. (deposition date: 2022-02-14, release date: 2023-02-15, Last modification date: 2023-08-30) |
Primary citation | Hashimoto, K.,Watanabe, S.,Akutsu, M.,Muraki, N.,Kamishina, H.,Furukawa, Y.,Yamanaka, K. Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation. J.Biol.Chem., 299:104798-104798, 2023 Cited by PubMed: 37156398DOI: 10.1016/j.jbc.2023.104798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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