7WX1

E40K/M117L variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)

Summary for 7WX1

Entry DOI	10.2210/pdb7wx1/pdb
Descriptor	Superoxide dismutase [Cu-Zn], ZINC ION, COPPER (II) ION, ... (4 entities in total)
Functional Keywords	superoxide dismutase, sod, sod1, oxidoreductase e40km117l, metal binding protein
Biological source	Canis lupus familiaris (dog)
Total number of polymer chains	2
Total formula weight	31951.38
Authors	Narikiyo, S.,Furukawa, Y.,Akutsu, M. (deposition date: 2022-02-14, release date: 2023-02-15, Last modification date: 2023-08-30)
Primary citation	Hashimoto, K.,Watanabe, S.,Akutsu, M.,Muraki, N.,Kamishina, H.,Furukawa, Y.,Yamanaka, K. Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation. J.Biol.Chem., 299:104798-104798, 2023 Cited by PubMed: 37156398 DOI: 10.1016/j.jbc.2023.104798 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation