8IQ1

Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state

Summary for 8IQ1

• Entry DOI: 10.2210/pdb8iq1/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], COPPER (II) ION, ZINC ION, ... (9 entities in total)
• Functional Keywords: dimer, oxidoreductase
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 8
• Total formula weight: 127370.19

Authors

Zhou, J.H.,Huang, W.X.,Cheng, R.X.,Zhang, P.J.,Zhu, Y.C. (deposition date: 2023-03-15, release date: 2023-09-06)

• Primary citation: Wu, D.D.,Jin, S.,Cheng, R.X.,Cai, W.J.,Xue, W.L.,Zhang, Q.Q.,Yang, L.J.,Zhu, Q.,Li, M.Y.,Lin, G.,Wang, Y.Z.,Mu, X.P.,Wang, Y.,Zhang, I.Y.,Zhang, Q.,Chen, Y.,Cai, S.Y.,Tan, B.,Li, Y.,Chen, Y.Q.,Zhang, P.J.,Sun, C.,Yin, Y.,Wang, M.J.,Zhu, Y.Z.,Tao, B.B.,Zhou, J.H.,Huang, W.X.,Zhu, Y.C.; Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.; Cell Rep, 42:112750-112750, 2023; PubMed: 37421623; DOI: 10.1016/j.celrep.2023.112750

Experimental method

X-RAY DIFFRACTION (1.8 Å)