8OL7
 
 | | MurineArc type I Abeta fibril from tg-APPArcSwe mouse | | 分子名称: | Amyloid-beta protein 42 | | 著者 | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | | 登録日 | 2023-03-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
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1A9W
 | | HUMAN EMBRYONIC GOWER II CARBONMONOXY HEMOGLOBIN | | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), ... | | 著者 | Sutherland-Smith, A.J, Baker, H.M, Hofmann, O.M, Brittain, T, Baker, E.N. | | 登録日 | 1998-04-11 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution.
J.Mol.Biol., 280, 1998
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8H5T
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1A5Z
 | | LACTATE DEHYDROGENASE FROM THERMOTOGA MARITIMA (TMLDH) | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, CADMIUM ION, L-LACTATE DEHYDROGENASE, ... | | 著者 | Auerbach, G, Ostendorp, R, Prade, L, Korndoerfer, I, Dams, T, Huber, R, Jaenicke, R. | | 登録日 | 1998-02-18 | | 公開日 | 1999-03-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.
Structure, 6, 1998
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8OLG
 | | DI2 Abeta fibril from tg-SwDI mouse | | 分子名称: | Amyloid-beta protein 42 | | 著者 | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | | 登録日 | 2023-03-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
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8OLO
 | | Murine type III Abeta fibril from ARTE10 mouse | | 分子名称: | Amyloid-beta protein 42 | | 著者 | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | | 登録日 | 2023-03-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
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8ON2
 | | NI,FE-CODH -600mV state : 24 h Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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7SAC
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8OMY
 | | NI,FE-CODH -600mV state : 35 min Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, FE (II) ION, FE (III) ION, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8ONS
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1ACA
 | | THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A | | 分子名称: | ACYL-COENZYME A BINDING PROTEIN, COENZYME A, PALMITIC ACID | | 著者 | Kragelund, B.B, Andersen, K.V, Madsen, J.C, Knudsen, J, Poulsen, F.M. | | 登録日 | 1992-11-17 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-04-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A.
J.Mol.Biol., 230, 1993
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1ADQ
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8OLL
 | | Staphylococcus aureus ClpP in complex with the natural product beta-lactone inhibitor Cystargolide A at 2.7 A resolution | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, Cystargolide A (bound) | | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | | 登録日 | 2023-03-30 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8ON3
 | | NI,FE-CODH -320mV + CN state : 24 h Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8OMX
 | | NI,FE-CODH -600mV state : 1 min Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, FE (II) ION, FE(4)-NI(1)-S(5) CLUSTER, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8ON1
 | | NI,FE-CODH -600mV state : 4 h Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, FE (II) ION, FE (III) ION, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8ORK
 | | cyclic 2,3-diphosphoglycerate synthetase from the hyperthermophilic archaeon Methanothermus fervidus | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | De Rose, S.A, Isupov, M. | | 登録日 | 2023-04-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus .
Front Microbiol, 14, 2023
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8ON0
 | | NI,FE-CODH -600mV state : 90 min Dioxygen Exposure | | 分子名称: | Carbon monoxide dehydrogenase 2, FE (II) ION, FE (III) ION, ... | | 著者 | Basak, Y, Jeoung, J.-H, Dobbek, H. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Stepwise O 2 -Induced Rearrangement and Disassembly of the [NiFe 4 (OH)( mu 3 -S) 4 ] Active Site Cluster of CO Dehydrogenase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8OLR
 | | Structure of yeast 20S proteasome in complex with the natural product beta-lactone inhibitor Cystargolide A | | 分子名称: | CHLORIDE ION, Cystargolide A (bound), MAGNESIUM ION, ... | | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | | 登録日 | 2023-03-30 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8ORU
 | | cyclic 2,3-diphosphoglycerate synthetase from the hyperthermophilic archaeon Methanothermus fervidus bound to 2,3-diphosphoglycerate and ADP. | | 分子名称: | (2R)-2,3-diphosphoglyceric acid, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | De Rose, S.A, Isupov, M. | | 登録日 | 2023-04-17 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus .
Front Microbiol, 14, 2023
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8P8G
 | | Nitrogenase MoFe protein from A. vinelandii beta double mutant D353G/D357G | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ... | | 著者 | Maslac, N, Wagner, T. | | 登録日 | 2023-06-01 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The Mononuclear Metal-Binding Site of Mo-Nitrogenase Is Not Required for Activity.
Jacs Au, 3, 2023
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8ORV
 | | Crystal structure of monkeypox virus poxin in complex with the STING agonist MD1203 | | 分子名称: | 9-[(1~{S},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, MPXVgp165 | | 著者 | Duchoslav, V, Klima, M, Boura, E. | | 登録日 | 2023-04-17 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure, 32, 2024
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8P44
 | | Crystal structure of monkeypox virus poxin in complex with the STING agonist MD1202D | | 分子名称: | 9-[(1~{S},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, MPXVgp165 | | 著者 | Duchoslav, V, Klima, M, Boura, E. | | 登録日 | 2023-05-19 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure, 32, 2024
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8OVY
 | | Structure of analogue of superfolded GFP | | 分子名称: | Green fluorescent protein | | 著者 | Dunkelmann, D, Fiedler, M, Bellini, D, Alvira, C.P, Chin, J.W. | | 登録日 | 2023-04-26 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.537 Å) | | 主引用文献 | Adding alpha , alpha-disubstituted and beta-linked monomers to the genetic code of an organism.
Nature, 625, 2024
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8OOJ
 | | Crystal structure of dCK C4S-S74E mutant in complex with EdC and UDP | | 分子名称: | 4-azanyl-1-[(2~{R},4~{S},5~{R})-5-ethynyl-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]pyrimidin-2-one, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Saez-Ayala, M, Rebuffet, E, Betzi, S, Morelli, X. | | 登録日 | 2023-04-05 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Mol.Cancer Ther., 23, 2024
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