8OLG

DI2 Abeta fibril from tg-SwDI mouse

Summary for 8OLG

Entry DOI	10.2210/pdb8olg/pdb
EMDB information	16957
Descriptor	Amyloid-beta protein 42 (1 entity in total)
Functional Keywords	amyloid fibril, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	5
Total formula weight	22590.58
Authors	Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroeder, G.F. (deposition date: 2023-03-30, release date: 2023-11-29, Last modification date: 2023-12-13)
Primary citation	Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Schafer, L.U.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroder, G.F. Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26:2073-2080, 2023 Cited by PubMed: 37973869 DOI: 10.1038/s41593-023-01484-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation