7SAC

S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution

Summary for 7SAC

Entry DOI	10.2210/pdb7sac/pdb
Related	7SAA 7SAB 7SAD
EMDB information	24946 24947 24948 24949
Descriptor	Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	ligand-gated ion channel, ionotropic glutamate receptor, synaptic protein, voltage-gate ion channel, transport protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	4
Total formula weight	391733.43
Authors	Chou, T.-H.,Furukawa, H. (deposition date: 2021-09-22, release date: 2022-07-20, Last modification date: 2022-10-26)
Primary citation	Chou, T.H.,Epstein, M.,Michalski, K.,Fine, E.,Biggin, P.C.,Furukawa, H. Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29:507-518, 2022 Cited by PubMed: 35637422 DOI: 10.1038/s41594-022-00772-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.69 Å)

Structure validation