8H5T
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-015
Summary for 8H5T
Entry DOI | 10.2210/pdb8h5t/pdb |
Descriptor | Spike protein S1, Nanobody Nb-015, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | viral protein, immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 2 |
Total formula weight | 39004.55 |
Authors | |
Primary citation | Yang, J.,Lin, S.,Chen, Z.,Yang, F.,Guo, L.,Wang, L.,Duan, Y.,Zhang, X.,Dai, Y.,Yin, K.,Yu, C.,Yuan, X.,Sun, H.,He, B.,Cao, Y.,Ye, H.,Dong, H.,Liu, X.,Chen, B.,Li, J.,Zhao, Q.,Lu, G. Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization. Plos Pathog., 19:e1011804-e1011804, 2023 Cited by PubMed: 38033141DOI: 10.1371/journal.ppat.1011804 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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