8ONS

TAF15 amyloid fold in atypical FTLD - Individual 1

Summary for 8ONS

Entry DOI	10.2210/pdb8ons/pdb
EMDB information	16999
Descriptor	TATA-binding protein-associated factor 2N (2 entities in total)
Functional Keywords	amyloid, amyloid-forming protein, neurodegeneration, rna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	5
Total formula weight	309545.00
Authors	Tetter, S.,Ryskeldi-Falcon, B. (deposition date: 2023-04-03, release date: 2023-12-06, Last modification date: 2024-02-07)
Primary citation	Tetter, S.,Arseni, D.,Murzin, A.G.,Buhidma, Y.,Peak-Chew, S.Y.,Garringer, H.J.,Newell, K.L.,Vidal, R.,Apostolova, L.G.,Lashley, T.,Ghetti, B.,Ryskeldi-Falcon, B. TAF15 amyloid filaments in frontotemporal lobar degeneration. Nature, 625:345-351, 2024 Cited by PubMed: 38057661 DOI: 10.1038/s41586-023-06801-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (1.97 Å)

Structure validation