Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4Y6D
DownloadVisualize
BU of 4y6d by Molmil
Factor Xa complex with GTC000101
分子名称: 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxopyrrolidin-1-yl]-3-fluoro-N,N-dimethylbenzamide, Coagulation factor X
著者Convery, M.A.
登録日2015-02-12
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献TBA
To Be Published
4WMA
DownloadVisualize
BU of 4wma by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese,acceptor ligand and UDP-Glucose
分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
著者Yu, H, Li, H.
登録日2014-10-08
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WNH
DownloadVisualize
BU of 4wnh by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese,acceptor ligand and UDP-Xylose
分子名称: Coagulation factor IX, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ...
著者Yu, H, Li, H.
登録日2014-10-11
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese,acceptor ligand and UDP-Xylose
To Be Published
4WM0
DownloadVisualize
BU of 4wm0 by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with acceptor ligand
分子名称: Coagulation factor IX, Xyloside xylosyltransferase 1, alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose
著者Yu, H, Li, H.
登録日2014-10-08
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WN2
DownloadVisualize
BU of 4wn2 by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex III)
分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
著者Yu, H, Li, H.
登録日2014-10-10
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WMI
DownloadVisualize
BU of 4wmi by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex I)
分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
著者Yu, H, Li, H.
登録日2014-10-09
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WMK
DownloadVisualize
BU of 4wmk by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex II)
分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
著者Yu, H, Li, H.
登録日2014-10-09
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WMB
DownloadVisualize
BU of 4wmb by Molmil
crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, acceptor ligand and UDP
分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
著者Yu, H, Li, H.
登録日2014-10-08
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
5BO1
DownloadVisualize
BU of 5bo1 by Molmil
Crystal structure of a human Jag1 fragment in complex with an anti-Jag1 Fab
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Payandeh, J, de Leon-Boenig, G.
登録日2015-05-26
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Nature, 528, 2015
4Z6A
DownloadVisualize
BU of 4z6a by Molmil
Crystal Structure of a FVIIa-Trypsin Chimera (YT) in Complex with Soluble Tissue Factor
分子名称: CALCIUM ION, CITRIC ACID, Coagulation factor VII, ...
著者Sorensen, A.B, Svensson, L.A, Gandhi, P.S.
登録日2015-04-04
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.
J.Biol.Chem., 291, 2016
4ZMA
DownloadVisualize
BU of 4zma by Molmil
Crystal Structure of a FVIIa-Trypsin Chimera (ST) in Complex with Soluble Tissue Factor
分子名称: CACODYLATE ION, CALCIUM ION, Coagulation factor VII, ...
著者Sorensen, A.B, Svensson, L.A, Gandhi, P.S.
登録日2015-05-02
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.
J.Biol.Chem., 291, 2016
4YLQ
DownloadVisualize
BU of 4ylq by Molmil
Crystal Structure of a FVIIa-Trypsin Chimera (FT) in Complex with Soluble Tissue Factor
分子名称: CALCIUM ION, Coagulation factor VII, N-PROPANOL, ...
著者Sorensen, A.B, Svensson, L.A, Gandhi, P.S.
登録日2015-03-05
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.
J.Biol.Chem., 291, 2016
4ZHA
DownloadVisualize
BU of 4zha by Molmil
Factor Xa complex with GTC000102
分子名称: 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxo-2,3-dihydro-1H-pyrrol-1-yl]-3-fluoro-N-methylbenzamide, CALCIUM ION, Coagulation factor X, ...
著者Convery, M.A.
登録日2015-04-24
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Factor Xa complex with GTC000102
To Be Published
4ZH8
DownloadVisualize
BU of 4zh8 by Molmil
Factor Xa complex with GTC000006
分子名称: 6-chloro-N-{(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxo-2,3-dihydro-1H-pyrrol-3-yl}-N-(2-oxobutyl)naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X
著者Convery, M.A.
登録日2015-04-24
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Factor Xa complex with GTC000006
To Be Published
5FDQ
DownloadVisualize
BU of 5fdq by Molmil
Murine COX-2 S530T mutant
分子名称: 2-[(2~{R})-2-(hydroxymethyloxy)propoxy]ethanol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lucido, M.J, Orlando, B.J, Malkowski, M.G.
登録日2015-12-16
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry.
Biochemistry, 55, 2016
5FMA
DownloadVisualize
BU of 5fma by Molmil
human Notch 1, EGF 4-7
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
登録日2015-11-02
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
5FM9
DownloadVisualize
BU of 5fm9 by Molmil
human Notch 1, EGF 4-7
分子名称: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
著者Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
登録日2015-11-02
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
5F86
DownloadVisualize
BU of 5f86 by Molmil
Crystal structure of Drosophila Poglut1 (Rumi) complexed with its substrate protein (EGF repeat)
分子名称: Coagulation factor IX, GLYCEROL, O-glucosyltransferase rumi, ...
著者Yu, H.J, Li, H.L.
登録日2015-12-09
公開日2016-07-20
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.
Nat. Chem. Biol., 12, 2016
5F84
DownloadVisualize
BU of 5f84 by Molmil
Crystal structure of Drosophila Poglut1 (Rumi) complexed with its glycoprotein product (glucosylated EGF repeat) and UDP
分子名称: Coagulation factor IX, O-glucosyltransferase rumi, SULFATE ION, ...
著者Yu, H.J, Li, H.L.
登録日2015-12-09
公開日2016-07-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.
Nat. Chem. Biol., 12, 2016
5F85
DownloadVisualize
BU of 5f85 by Molmil
Crystal structure of Drosophila Poglut1 (Rumi) complexed with its substrate protein (EGF repeat) and UDP
分子名称: Coagulation factor IX, GLYCEROL, O-glucosyltransferase rumi, ...
著者Yu, H.J, Li, H.L.
登録日2015-12-09
公開日2016-07-20
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.
Nat. Chem. Biol., 12, 2016
5JVY
DownloadVisualize
BU of 5jvy by Molmil
Crystal structure of S121P murine COX-2 mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, ...
著者Orlando, B.J, Malkowski, M.G, Dong, L.
登録日2016-05-11
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit.
J.Biol.Chem., 291, 2016
5JVZ
DownloadVisualize
BU of 5jvz by Molmil
Crystal structure of flurbiprofen bound to S121P murine COX-2 mutant
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Malkowski, M.G, Orlando, B.J.
登録日2016-05-11
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit.
J.Biol.Chem., 291, 2016
5JW1
DownloadVisualize
BU of 5jw1 by Molmil
Crystal structure of Celecoxib bound to S121P murine COX-2 mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, ...
著者Malkowski, M.G, Orlando, B.J.
登録日2016-05-11
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit.
J.Biol.Chem., 291, 2016
5UK5
DownloadVisualize
BU of 5uk5 by Molmil
Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Garcia, K.C, Luca, V.C.
登録日2017-01-19
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.
Science, 355, 2017
5KY2
DownloadVisualize
BU of 5ky2 by Molmil
mouse POFUT1 in complex with O-glucosylated mouse Factor VII EGF1 and GDP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor VII, GDP-fucose protein O-fucosyltransferase 1, ...
著者Li, Z, Rini, J.M.
登録日2016-07-20
公開日2017-05-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
Nat. Chem. Biol., 13, 2017

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon