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5F86

Crystal structure of Drosophila Poglut1 (Rumi) complexed with its substrate protein (EGF repeat)

Summary for 5F86
Entry DOI10.2210/pdb5f86/pdb
Related5F84 5F85 5F87
DescriptorO-glucosyltransferase rumi, Coagulation factor IX, GLYCEROL, ... (5 entities in total)
Functional Keywordsglycosyltransferase, protein o-glucosyltransferase, notch regulation, egf repeat, transferase-hydrolase complex, transferase/hydrolase
Biological sourceDrosophila melanogaster (Fruit fly)
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Cellular locationEndoplasmic reticulum lumen : Q8T045
Secreted : P00740
Total number of polymer chains2
Total formula weight53198.87
Authors
Yu, H.J.,Li, H.L. (deposition date: 2015-12-09, release date: 2016-07-20, Last modification date: 2018-04-18)
Primary citationYu, H.,Takeuchi, H.,Takeuchi, M.,Liu, Q.,Kantharia, J.,Haltiwanger, R.S.,Li, H.
Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.
Nat. Chem. Biol., 12:735-740, 2016
Cited by
PubMed: 27428513
DOI: 10.1038/nchembio.2135
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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