5UK5

Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)

Summary for 5UK5

• Entry DOI: 10.2210/pdb5uk5/pdb
• Related: 2VJ3 4CC0 4D0E 4XL1 4XLW
• Descriptor: Neurogenic locus notch homolog protein 1, Protein jagged-1, alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: notch, jagged, delta, glycoprotein, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 2
• Total formula weight: 59432.96

Authors

Garcia, K.C.,Luca, V.C. (deposition date: 2017-01-19, release date: 2017-03-08, Last modification date: 2023-10-04)

• Primary citation: Luca, V.C.,Kim, B.C.,Ge, C.,Kakuda, S.,Wu, D.,Roein-Peikar, M.,Haltiwanger, R.S.,Zhu, C.,Ha, T.,Garcia, K.C.; Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.; Science, 355:1320-1324, 2017; PubMed: 28254785; DOI: 10.1126/science.aaf9739

Experimental method

X-RAY DIFFRACTION (2.506 Å)