2VJ3

Human Notch-1 EGFs 11-13

Summary for 2VJ3

Related1TOZ 2F8Y 1YYH 1PB5 2F8X
DescriptorNEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, SODIUM ION, ... (5 entities in total)
Functional Keywordstranscription, metal-binding, transmembrane, developmental protein, notch signaling pathway, differentiation, phosphorylation, egf-like domain, transcription regulation, receptor, activator, ank repeat, signalling, polymorphism, glycoprotein, extracellular, egf, notch, jagged, nucleus, calcium, membrane
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total molecular weight15134.8
Authors
Johnson, S.,Cordle, J.,Tay, J.Z.,Roversi, P.,Lea, S.M. (deposition date: 2007-12-06, release date: 2008-07-29, Last modification date: 2017-07-05)
Primary citation
Cordle, J.,Johnson, S.,Tay, J.Z.,Roversi, P.,Wilkin, M.B.,De Madrid, B.H.,Shimizu, H.,Jensen, S.,Whiteman, P.,Jin, B.,Redfield, C.,Baron, M.,Lea, S.M.,Handford, P.A.
A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15:849-, 2008
PubMed: 18660822 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.1457
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25940.8%00.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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