2VJ3
Human Notch-1 EGFs 11-13
Summary for 2VJ3
Entry DOI | 10.2210/pdb2vj3/pdb |
Related | 1PB5 1TOZ 1YYH 2F8X 2F8Y |
Descriptor | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | transcription, metal-binding, transmembrane, developmental protein, notch signaling pathway, differentiation, phosphorylation, egf-like domain, transcription regulation, receptor, activator, ank repeat, signalling, polymorphism, glycoprotein, extracellular, egf, notch, jagged, nucleus, calcium, membrane |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 15134.80 |
Authors | Johnson, S.,Cordle, J.,Tay, J.Z.,Roversi, P.,Lea, S.M. (deposition date: 2007-12-06, release date: 2008-07-29, Last modification date: 2023-12-13) |
Primary citation | Cordle, J.,Johnson, S.,Tay, J.Z.,Roversi, P.,Wilkin, M.B.,De Madrid, B.H.,Shimizu, H.,Jensen, S.,Whiteman, P.,Jin, B.,Redfield, C.,Baron, M.,Lea, S.M.,Handford, P.A. A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition. Nat.Struct.Mol.Biol., 15:849-, 2008 Cited by PubMed: 18660822DOI: 10.1038/NSMB.1457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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