2VJ3

Human Notch-1 EGFs 11-13

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1	polymer	135	14857.6	1	UniProt (P46531) Pfam (PF07645) Pfam (PF00008)	HOMO SAPIENS (HUMAN)	NOTCH 1, HN1, TRANSLOCATION-ASSOCIATED NOTCH PROTEIN TAN-1, NOTCH-1
2	B, C, D, E (A)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	F, G (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	H, I (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	J (A)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A: 409 - 410 (PDB: 2VJ3)
A: 527 - 543 (PDB: 2VJ3)
A: 411 - 526 (UniProt: P46531)

PDB	External Database	Details
Ile 477	Met 477	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14857.6
Non-Polymers*	Number of molecules	8
	Total formula weight	277.2
All*	Total formula weight	15134.8

*Water molecules are not included.